Human Papillomavirus Protein E6-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Human Papillomavirus Protein E6 (E6) - The Human Papillomavirus (HPV) E6 protein is one of oncoproteins encoded by the virus. It is a 151 amino-acid peptide. It plays a major role in the induction and maintenance of cellular transformation. It acts mainly as an oncoprotein... more

Granulocyte Macrophage Colony Stimulating Factor-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Ganulocyte Macrophage Colony Stimulating Factor (GMCSF or Colony Stimulating Factor or CSF or Molgramostin or Sargramostim or CSF2) - Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a glycoprotein secreted by macrophages, T cells, mast cells, NK cells,... more

Beta Nerve Growth Factor-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Beta Nerve Growth Factor (Beta NGF or NGF) - Nerve growth factor is a neurotrophic factor involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. Report Highlights Beta Nerve Growth Factor (Beta NGF or NGF)... more

Protein Kinase C Theta Type-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Protein Kinase C Theta Type (nPKC Theta or PRKCQ or EC 2.7.11.13) - Protein kinase C theta (PKC-θ) is an enzyme encoded by the PRKCQ gene. It mediates non-redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation... more

Phosphatidylinositol 45 Bisphosphate 3 Kinase Catalytic Subunit Alpha Isoform-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Phosphatidylinositol 4,5 Bisphosphate 3 Kinase Catalytic Subunit Alpha Isoform (Phosphatidylinositol 4,5 Bisphosphate 3 Kinase 110 kDa Catalytic Subunit Alpha or Phosphoinositide 3 Kinase Catalytic Alpha Polypeptide or Serine/Threonine Protein Kinase PIK3CA or PIK3CA... more

Caspase 3-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Caspase 3 (Apopain or Cysteine Protease CPP32 or Protein Yama or SREBP Cleavage Activity 1 or CASP3 or EC 3.4.22.56) - Caspase-3 is a caspase protein encoded by the CASP3 gene. It interacts with caspase-8 and caspase-9. It cleaves and activates sterol regulatory element... more

Nitric Oxide Synthase Brain-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Nitric Oxide Synthase Brain (Constitutive NOS or NC NOS or Neuronal NOS or bNOS or NOS Type I or Peptidyl Cysteine S Nitrosylase NOS1 or NOS1 or EC 1.14.13.39) - Nitric oxide synthase 1 or NOS1 is an enzyme encoded by the NOS1 gene. It produces nitric oxide (NO) which... more

Serine/Threonine Protein Kinase PLK1-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Serine/Threonine Protein Kinase PLK1 (Polo Like Kinase 1 or Serine/Threonine Protein Kinase 13 or PLK1 or EC 2.7.11.21) - Serine/threonine-protein kinase PLK1 is an enzyme encoded by the PLK1 (polo-like kinase 1) gene. It is highly expressed during mitosis and elevated... more

Serine/Threonine Protein Kinase Pim 2-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Serine/Threonine Protein Kinase Pim 2 (Pim 2h or Proto Oncogene Pim 2 or PIM2 or EC 2.7.11.1) - Serine/threonine-protein kinase Pim-2 is an enzyme encoded by the PIM2. It is involved in cell survival and cell proliferation. It regulates cap-dependent protein translation... more

Chronic Lymphocytic Leukemia-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Chronic lymphocytic leukemia (CLL) is a type of cancer that starts from white blood cells (called lymphocytes) in the bone marrow. It then invades the blood. Symptoms usually develop slowly. Symptoms of CLL include abnormal bruising (if platelets are low) , fever,... more

Non-Hodgkin Lymphoma-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Non-Hodgkin lymphoma (also known as non-Hodgkin lymphoma, NHL, or sometimes just lymphoma) is a cancer that starts in cells called lymphocytes, which are part of the body's immune system. Symptoms depend on what area of the body is affected by the cancer and how fast... more

Chondrosarcoma-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Chondrosarcoma is a malignant cancer whose tumor cells produce a pure hyaline cartilage that results in abnormal bone and/or cartilage growth. Signs and symptoms include pain in the affected area that may worsen at night or during physical activity, swelling in the... more

Hepcidin-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Hepcidin (Liver Expressed Antimicrobial Peptide 1 or Putative Liver Tumor Regressor or HAMP) - Hepcidin is a protein encoded by the HAMP gene. It acts by promoting endocytosis and degradation of ferroportin leading to the retention of iron in iron exporting cells and... more

Ewing Sarcoma-Pipeline Review H1 2017

(EMAILWIRE.COM, June 17, 2017 ) Ewing's sarcoma is a primary bone cancer that affects mainly children and adolescents. Ewing's sarcoma can occur any time during childhood and young adulthood, but usually develops during puberty, when bones are growing rapidly. There are few symptoms. The most common... more

Anaplastic Astrocytoma-Pipeline Review H2 2017

(EMAILWIRE.COM, June 17, 2017 ) Anaplastic astrocytoma is a grade III tumor. It accounts for two percent of all brain tumors. It is a type of glioma that develops from star-shaped glial cells (astrocytes) , which support nerve cells. Anaplastic astrocytoma grows faster and more aggressively than... more